Onglyza and Kombiglyze XR Lawsuit Attorneys

Lawyers for Onglyza and Kombiglyze XR Claims

Kombiglyze XR or Onglyza LawyersOnglyza (saxagliptin) and Kombiglyze XR (saxagliptin and metformin HCI extended-release) are Type 2 diabetes medications manufactured jointly by AstraZeneca and Bristol-Myers Squibb. Onglyza was approved in 2009, with Kombiglyze XR following in 2010. These medications are designed to control high blood sugar in certain type 2 diabetics. If you or a loved one was injured from using Onglyza or Kombiglyze XR, call us to speak to a Onglyza lawsuit lawyer or a Kombiglyze XR lawsuit lawyer for a free consultation: 800-298-0111.

What is Onglyza and Kombiglyze XR?

Onglyza and Kombiglyze both contain the active ingredient saxagliptin, a DPP-4 inhibitor used to prevent the hormone GLP-1 from being broken down. This is because GLP-1 signals the pancreas to make insulin, and inhibiting DPP-4 allows the hormone to stay in the body longer, resulting in more insulin. Onglyza not only helps the body produce more insulin, but it also reduces the amount of other hormones released in the pancreas, and as a result, prevents the liver from making too much glucose. Because Kombiglyze contains metformin, it also controls blood sugar by decreasing sugar absorbed in the stomach and reducing sugar produced by the liver.

Onglyza and Kombiglyze XR FDA Warnings

Since its approval in 2009, the FDA has released 3 drug safety communications about Onglyza and Kombiglyze XR. In 2013, they said the drugs increase the risk of inflammation of the pancreas (pancreatitis) and found pre-cancerous signs in the pancreas. In 2015, they released that the drugs may cause severe to disabling joint pain. The last safety communication released about Onglyza and Kombiglyze was on April 5, 2016, when the FDA identified the risk of heart failure.

Onglyza and Kombiglyze XR Cardiac Lawsuits

Most lawsuits against AstraZeneca and Bristol-Myers Squibb allege that the manufacturers failed to warn medical providers and patients of the cardiac issues Onglyza and Kombiglyze XR may cause. Serious injuries include congestive heart failure, cardiac arrest and death.

Onglyza and Kombiglyze XR Attorneys

If you or someone you know was prescribed Onglyza or Kombiglyze XR before April 5, 2016 and have suffered severe injuries, you may be entitled to damages. Simmons and Fletcher, P.C. has been helping victims understand their rights for more than 40 years. Call us to speak to a Onglyza lawsuit lawyer or a Kombiglyze XR lawsuit lawyer today at 800-298-0111.

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Paul Cannon

Paul Cannon has practiced personal injury trial law since 1995. He is Board Certified in Personal Injury Trial Law (2005). He has earned recognition as a Super Lawyer by Thompson Reuters in 2017 & 2018, and as a Top 100 Trial Lawyer by the National Trial Lawyers Association in 2017. He is a Shareholder, trial lawyer and online marketing manager at Simmons and Fletcher, P.C. His legal writings have been published by the Texas Bar Journal,, HG Legal Resources,, and others. He has been asked to give education talks and media interviews on dog bite law.